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. Author manuscript; available in PMC: 2012 Jun 5.
Published in final edited form as: Prog Retin Eye Res. 2011 Mar 2;30(3):167–187. doi: 10.1016/j.preteyeres.2011.02.003

Fig. 19.

Fig. 19

VEPs (panels A and D) and pERGs (panels B and E) recorded from a rhesus monkey 1 week (top) and 9 weeks (bottom) following induction of pNAION. Results for the experimental eye (red lines) and control eye (blue lines) are plotted. The VEP is reduced by about 30% in the induced eye at 1 week and does not show further decline at 9 weeks. Conversely, the pERG is normal at 1 week post-induction, but shows a large loss in the N95 component (originating in spiking cells) and a smaller loss in P50 (from a combination of spiking and non-spiking cells) at 9 weeks post-induction, indicating the expected delayed impairment of ganglion cell function. The panels on the right are ganzfeld ERGs recorded 5 h (top panel C) and 13 weeks (Bottom panel F) after induction. The results indicate that there were no gross short-term or long-term pre-ganglion cell changes in the retina as a result of laser induction.