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. 2012 Jul 1;139(13):2299–2307. doi: 10.1242/dev.078873

Fig. 7.

Fig. 7.

Astrocyte differentiation from postnatal NG2 cells in Olig2 iCko neocortex. (A,B) Triple labeling for GFP (green), Olig2 (red) and GS (blue) in the neocortex of NG2creER:YFP:Olig2fl/fl (iCko, A) and NG2creER:YFP:Olig2fl/+ (iCtr, B) mice 30 days after Cre induction at P2-5. Arrowheads in A indicate YFP+ GS+ astrocytes that are the progeny of NG2 cells in iCko brain. Other YFP+ cells in iCko cortex have the polydendrocyte morphology (arrow in A). All the YFP+ cells in iCtr cortex (B) are Olig2+ and GS– (arrows). Scale bars: 20 μm. (C) The proportion of astrocytes among Olig2-deleted progeny of NG2 cells. Data are the percentage of YFP+ GS+ Olig2– cells among all YFP+ Olig2– cells in iCko cortex at 14 and 30 dpi. The values for iCtr cortex were 0% at both time points. Error bars indicate s.d.