Figure 3.

VMY-induced disruption of mitosis in DAOY cells. Live cell imaging was performed using stably transfected DAOY/GFP-H2B cells. (A) The percent of cells that successfully completed mitosis within 6 h following release from nocodazole block. (B) Metaphase transit time. (C) Examples of transit times of cells that successfully progressed through metaphase. Data are average percent change (+ SD, n > 250 cells, two separate experiments). Arrows, significant changes in mitotic progression in VMY vs. Flavo (flavopiridol) treated cells.