Clinical EAE after antigenic challenge | |||
Challenge antigen doses (μg/mouse) | Incidence | Av. disease grade (range) | Av. day of onset (range) |
200 | 4/4 | 3.75 (3-4) | 8.25 (7-9) |
100 | 4/4 | 3.67 (3-4) | 7.5 (7-8) |
50 | 4/4 | 3.25 (3-4) | 8.25 (7-10) |
25 | 4/4 | 3.0 (3.0) | 8.25 (8-9) |
10 | 4/4 | 3.0 (3.0) | 8.76 (8-9) |
5 | 4/4 | 2.5 (2-3) | 9.75 (9-10) |
1 | 2/4 | 1.0 (1.0) | 16 (14-18) |
0 | 0/4 | - - | - - |