Table 1.
Vh act (mV) |
Time to peak act (ms) |
Act time constant |
Vh inact (mV) |
||
---|---|---|---|---|---|
Kvα1.5WT | alone | −6.5 ± 0.26 | 62 ± 14 | 1.7 ± 0.3 | --a |
+β3 | −19.7 ± 0.6* | 7.1 ± 0.5* | 1.5 ± 0.4 | −22.2 ± 0.9 | |
Kvα1.5ΔC56 | alone | −3.2 ± 0.6† | 22 ± 4.4† | 1.1 ± 0.2 | --a |
+β3 | −21.5 ± 1.5* | 6.0 ± 0.6* | 1.1 ± 0.2 | −20.5 ± 0.3 |
Due to minimal inactivation, the kinetics and the voltage-dependence of inactivation of Kvα currents could not be reliably estimated
P<0.05 Kvα1.5 (WT or ΔC) alone versus coexpressed with Kvβ3
P<0.05 Kvα1.5WT versus Kvα1.5ΔC56