Table 2.
Odds ratio (OR) and 95% confidence interval (CI) for outcomes of interest by cohort and at-risk group
| MBT | Outcome | % Cohort | % Control | OR | P |
|---|---|---|---|---|---|
| All pregnancies | Mortality | <10 | 0.02 | 143 (71–288) | † |
| Non-delivery | 56.5 | 13.1 | 8.6 (7.0–10.5)a | † | |
| Hyperemesis | <10 | 1.1 | 2.2 (1.1–4.3) | .001 | |
| Deliveries | Mortality | <10 | 0.01 | 326 (134–796) | † |
| Preterm labor | 19.4 | 6.9 | 3.4 (2.3–5.1)b | † | |
| IUGR | <10 | 1.5 | 2.9 (1.4–6.2) | .01 | |
| Stillbirth | <10 | 0.48 | 3.9 (1.2–12) | .05 | |
| Caesarean | 64.9 | 25.7 | 6.4 (4.5–9.0)c | † | |
| BBT | Outcome | % Cohort | % Control | OR | P |
| All pregnancies | Mortality | <10 | 0.02 | 15 (2.1–108) | .06 |
| Non-delivery | 39.4 | 13.1 | 4.3 (3.5–5.2)a | † | |
| Hyperemesis | 3.0 | 1.1 | 2.8 (1.6–4.9) | .001 | |
| Deliveries | Preterm labor | 15.9 | 6.9 | 2.3 (1.6–3.3)d | † |
| IUGR | <10 | 1.5 | 1.8 (0.8–3.8) | .13 | |
| Stillbirth | <10 | 0.48 | 1.6 (0.4–6.4) | .36 | |
| Caesarean | 49.4 | 25.7 | 2.8 (2.1–3.6)e | † | |
| ST | Outcome | % Cohort | % Control | OR | P |
| All pregnancies | Non-delivery | 36.4 | 13.1 | 3.8 (2.0–7.0)f | † |
| Deliveries | Preterm labor | <10 | 6.9 | 2.3 (0.8–6.5) | .12 |
| IUGR | <10 | 1.5 | 5.0 (1.2–21.1) | .07 | |
| Caesarean | 57.1 | 25.7 | 3.9 (1.8–8.2) | † |
Abbreviations: MBT, malignant brain tumors; BBT, benign brain tumors; ST, spine tumors; IUGR, intrauterine growth restriction.
Outcomes are not reported for subgroups with zero events. ORs are univariate unless otherwise noted.
aAdjusted for age, pre-eclampsia, chronic and gestational diabetes, chronic and gestational hypertension, renal disease, multiple gestation, race, and socioeconomic status.
bAdjusted for pre-eclampsia, multiple gestation, and race.
cAdjusted for age, year, previous Caesarean delivery, pre-eclampsia, chronic and gestational diabetes, chronic and gestational hypertension, multiple gestation, and insurance payor.
dAdjusted for pre-eclampsia, chronic diabetes, multiple gestation, and race.
eAdjusted for age, year, previous Caesarean delivery, pre-eclampsia, chronic and gestational diabetes, chronic and gestational hypertension, multiple gestation, renal disease, insurance payor, socioeconomic status, and hospital type.
fAdjusted for chronic diabetes and race.
†P < .0001