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. 2012 Apr 25;14(6):798–807. doi: 10.1093/neuonc/nos081

Table 1.

Patient clinical features and treatment characteristics in the whole group and in the 2 subgroups according to postoperative treatment

Characteristics Total RT Alone RT + CHT Chi-square P
n (%) n (%) n (%)
295 (100) 97 (32.9) 198 (67.1)
Age
 ≤50 years 123 (41.7) 36 (37.1) 87 (43.9) 0.52
 51–60 years 63 (21.4) 23 (23.7) 40 (20.2)
 >60 years 109 (36.9) 38 (39.2) 71 (35.9)
Gender
 Male 192 (65.1) 65 (67.0) 127 (64.1) 0.62
 Female 103 (34.9) 32 (33.0) 71 (35.9)
Number of lesions
 Single 280 (94.9) 92 (94.8) 188 (94.9) 0.97
 Multiple 15 (5.1) 5 (5.2) 10 (5.1)
Presenting symptoms
 Focal symptoms 194 (65.7) 63 (64.9) 131 (66.2) 0.84
 Cranial hypertension 76 (25.8) 39 (40.2) 46 (23.2) 0.15
 Seizure 98 (33.2) 28 (28.9) 70 (35.4) 0.27
 None 2 (0.7)
Preoperative KPS
 90–100 110 (37.3) 23 (23.7) 47 (23.7) 0.14
 80 116 (39.3) 41 (42.3) 75 (37.9)
 ≤70 69 (23.4) 33 (34.0) 36 (18.2)
Postoperative KPS
 90–100 161 (54.6) 41 (42.3) 120 (60.6) 0.002
 80 60 (20.3) 20 (20.6) 40 (20.2)
 <70 74 (25.1) 36 (37.1) 38 (19.2)
RPA class
 I 93 (31.6) 27 (27.8) 66 (33.3) 0.19
 II 24 (8.1) 6 (6.2) 18 (9.1)
 III 42 (14.2) 15 (15.5) 27 (13.6)
 IV 82 (27.8) 24 (24.7) 58 (29.3)
 V 54 (18.3) 25 (25.8) 29 (14.6)
 VI
RPA classes 1–3 vs 4–5
 I–III 159 (53.9) 48 (49.5) 111 (56.1) 0.29
 IV–V 136 (46.1) 49 (50.5) 87 (43.9)
RPA classes 1–2 vs 3 vs 4–5
 I–II 117 (39.7) 33 (23.7) 84 (42.4) 0.38
 III 42 (14.2) 15 (76.3) 27 (13.6)
 IV–V 136 (46.1) 49 (50.5) 87 (43.9)
Surgical procedure
 Biopsy 70 (23.7) 23 (23.7) 47 (23.7) 1.00
 Exeresis 225 (76.3) 74 (76.3) 151 (76.3)
3D-CRT
 Yes 254 (86.1) 73 (75.3) 181 (91.4) 0.002
 No 41 (13.9) 24 (24.7) 17 (8.6)
RT fraction size
 1.8 Gy 19 (6.4) 4 (4.1) 15 (7.6) 0.0007
 2 Gy 248 (84.1) 75 (77.3) 173 (87.4)
 3 Gy 28 (9.5) 18 (18.6) 10 (5.1)
RT total dose for 1.8/2 Gy per fraction
 <60 Gy 33 (11.2) 17 (17.5) 16 (8.1) 0.005
 60 Gy 178 (60.3) 43 (44.3) 135 (68.2)
 >60 Gy 56 (19.0) 19 (19.6) 37 (18.7)
RT total dose for 3 Gy per fraction
 ≤39 Gy 14 (4.7) 9 (9.3) 5 (2.5) 0.05
 >39 Gy 14 (4.7) 9 (9.3) 5 (2.5)
Delay of RT
 ≤45 days 114 (38.7) 31 (32.0) 83 (41.9) 0.13
 >45 days 124 (42.0) 45 (46.4) 79 (39.9)
 Unknown 57 (19.3)