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. 2012 Jun 5;7(6):e37868. doi: 10.1371/journal.pone.0037868

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Lyke et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Shown are the percentages of B memory cell responders to S. haematobium antigens, SEA and SWAP, as determined by ELISpot assay during the malaria transmission season and again during the dry season with significant differences demarcated. Results were stratified by age (A–C) and S. haematobium status [S. haematobium positive (SP) = 54 and S. haematobium negative (SN) = 29] Responders are defined to those individuals with antigen specific cell (ASC) ratios (ratio of spot forming cells (SFC)/10⁶ expanded cells vs. total IgG SFC/10⁶ cells) greater than 0.01.