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. 2012 Jun 5;7(6):e37868. doi: 10.1371/journal.pone.0037868

Table 1. Demographic characteristics at enrollment and features of P. falciparum clinical malaria episodes of Schistosoma haematobium-positive and age-matched S. haematobium-negative Malian children contributing PBMC for immunologic analysis.a .

Category Age (years) S. haematobium (+) S. haematobium (−) P value
Mean age (n) All ages 8.7 (54) 9.0 (30) ns
4–8 6.4 (27) 6.8 (15) ns
9–14 11.0 (27) 11.3 (15) ns
Female (%) 4–14 26 (48.1) 16 (53.3) ns
Eggs (range) a 4–14 58 (2–786) 0 n/a
4–8 51 (2–596) 0 n/a
9–14 66 (2–786) 0 n/a
Clinical malaria episodes b (n, range) 4–14 1.5 (1–4) 2.1 (1–4) 0.002
Days to first clinical malaria episode b (range) 4–14 76.2 (52–166) 26.4 (2–117) <0.0001 c
Parasitemia b,d (range) 4–14 9,299 (275–155,425) 11,785 (600–135,000) 0.87
a

Urinary egg excretion detected in 10 ml of filtered morning urine.

b

Results for children who did not develop malaria (n = 14) are not included these calculations. If no statistical difference was noted between children in the 4–8 year old category compared to the 9–14 year old category, the results were combined.

c

Multivariable Cox regression analysis used controlling for age and schistosoma status.

d

Geometric mean parasite density per mm3.