Skip to main content
. 2012 Jun 5;10(6):e1001337. doi: 10.1371/journal.pbio.1001337

Figure 8. Effects on circadian locomotor activity of altering AC3 in M pacemakers.

Figure 8

(A) Representative locomotor behavior of flies that are heterozygous for the AC3 locus (Df(2L)DS6). (B) Representative locomotor behavior of flies that combine a knockdown of AC3 by RNAi together with a deficiency for the AC3 locus. (C) Representative locomotor behavior of flies over-expressing AC3. (D) Representative locomotor behavior of flies over-expressing PDF-R and over-expressing AC3. Morning anticipation index was calculated as (sum of activity 3 h before lights-on)/(sum of activity 6 h before lights-on). The average morning anticipation index was calculated from three replicates for each genotype. Error bars denote SEM. *** p<0.001 (compared with control). Statistical analysis of morning anticipation is shown in Table 1, and behavioral outcomes for DD are shown in Table 2.