Table 2.

Sleep Parameters

	Study Phase
	Baseline	Acclimation	Satisfactory Dose Median	End of Study	p-value*	p-value**
Sleep Latency (minutes)	38.2	42.9	21.6	22.5	<0.0001	0.96
Sleep Efficiency (percent)	74.6	75.0	76.5	79.3	0.026	0.16
Wake Time After Sleep Onset (minutes)	57.6	64.9	70.5	68.6	0.022	0.31
Total Sleep Time (minutes)	442.7	450.1	459.0	457.3	0.011	0.18

^*comparing satisfactory dosing phase to acclimation dosing. Significance was adjusted for multiple comparisons (0.05/number of comparisons within a family of tests) with values meeting significance bolded.

^**comparing end of study dosing phase to satisfactory dosing phase