Table 3.
mLEEK is overexpressed in cancer tissues
| n | Staining intensity | ||||
|---|---|---|---|---|---|
| 3+ | 2+ | 1+ | 0 | ||
| Skin | |||||
| Normal | 5 | — | — | 80% | 20% |
| Melanoma | 30 | 10% | 37% | 53% | 0% |
| Lung | |||||
| Normal | 11 | — | 36% | — | 64% |
| Adenocarcinoma | 25 | 36% | 36% | 20% | 8% |
| Squamous | 26 | 4% | 23% | 46% | 27% |
| Ovary | |||||
| Normal | 3 | — | — | — | 100% |
| Adenocarcinoma | 31 | 52% | 35% | 13% | — |
Abbreviation: mLEEK, mini-LEEK.
Immunohistochemistry was performed with anti-mLEEK antibody on paraffin-embedded normal or tumor specimens. Staining intensity was evaluated by a surgical pathologist. Representative images are presented in Supplementary Figure 2.