TABLE II.
Variables | N | miR-20a | miR-21 | miR-145 | miR-221 |
---|---|---|---|---|---|
Age at diagnosis | |||||
< median (60 yr) | 35 | 7,324 | 830 | 117 | 798 |
≥ median (60 yr) | 47 | 2,978 | 551 | 108 | 748 |
p value | 0.20 | 0.35 | 0.80 | 0.78 | |
Ethnicity | |||||
Caucasian | 46 | 5,175 | 501 | 95 | 687 |
African-American | 10 | 2,368 | 465 | 90 | 726 |
Others | 26 | 5,174 | 1,049 | 153 | 945 |
p value | 0.86 | 0.21 | 0.30 | 0.44 | |
Family history of prostate cancer | |||||
No | 59 | 3,784 | 630 | 118 | 824 |
Yes | 20 | 2,023 | 445 | 65 | 538 |
p value | 0.27 | 0.49 | 0.17 | 0.18 | |
Prostate volume | |||||
< median (50) | 35 | 3,735 | 636 | 123 | 685 |
≥ median 50 | 36 | 6,806 | 829 | 128 | 868 |
p value | 0.43 | 0.57 | 0.90 | 0.39 | |
PSA levels (ng/ml) | |||||
< 6 | 51 | 3,850 | 689 | 109 | 709 |
≥ 6 | 24 | 7,630 | 748 | 125 | 955 |
p value | 0.34 | 0.87 | 0.70 | 0.24 | |
Tumor stage | |||||
T2a-T2c | 63 | 2,908 | 529 | 103 | 812 |
≥ T3 | 19 | 11,215 | 1,140 | 145 | 626 |
p value | 0.03 | 0.08 | 0.34 | 0.39 | |
Gleason sum score | |||||
6 | 24 | 2,541 | 379 | 63 | 705 |
7 | 39 | 6,311 | 790 | 132 | 818 |
8–9 | 19 | 4,692 | 792 | 126 | 739 |
p value | 0.63 | 0.45 | 0.21 | 0.86 | |
Follow-up time (months) | |||||
< median (19.8) | 38 | 6,141 | 599 | 106 | 817 |
≥ median (19.8) | 38 | 2,532 | 495 | 107 | 686 |
p value | 0.29 | 0.67 | 0.99 | 0.50 | |
Relapse status | |||||
No | 71 | 4,477 | 565 | 108 | 741 |
Yes | 5 | 2,348 | 295 | 83 | 901 |
p value | 0.76 | 0.58 | 0.76 | 0.70 | |
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