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. Author manuscript; available in PMC: 2012 Jun 6.
Published in final edited form as: Nature. 2011 Oct 19;479(7373):365–371. doi: 10.1038/nature10572

Fig. 5. Other longevity regulators do not have a transgenerational effect on lifespan.

Fig. 5

a–b, Lifespan of P0 (a) and F1 (b) generation descendents from worms treated with set-9, set-15, utx-1, and wdr-5 RNAi only in the P0 generation. Control RNAi: empty vector. c, Scheme for generating wildtype progeny from daf-2(e1370) mutant worms. d, Lifespan of genetically wildtype F3 descendents from daf-2(e1370) mutant worms (+/+ from P0 daf-2 parents). Mean lifespan and statistics are presented in Supplementary Tables 2 and 4.