Table 1.
Change in contour length (ΔL), rupture force (Funfold), free energy of unfolding (ΔGunfold), bias of ΔGunfold, and percentage formation (% formation) for fully folded tetraplex structures under different pH and ionic conditions at 23°C
| pH | Salt ions | ΔL (nm) | Funfold (pN) | ΔGunfold (kcal/mol) | Bias of ΔGunfold (kcal/mol) | % Formation |
|---|---|---|---|---|---|---|
| 7.4 | K+ | 6.7 (±0.2) | 24 (±1) | 7.8 (±1.4) | −0.5 | 18 |
| 5.5 | Li+ | 7.2 (±0.1) | 28 (±2) | 8.7 (±1.0) | 1.0 | 34 |
| 5.5 | K+ | 6.7 (±0.2) | 17 (±1) (left peak) | 7.4 (±0.5) (left peak) | 1.2 | 14 |
| 36 (±1) (right peak) | 10.4 (±1.2) (right peak) | 1.1 | 19 |
Values in parentheses are SDs.