Table 1.

Correlation between some RTNs cellular functions and their potential involvement in different human diseases.

Cellular functions	Human diseases
ER homeostasis	Cancer and neurodegenerative disorders (i.e., ALS, Alzheimer's disease)
Calcium homeostasis	Neuronal pathologies (i.e., schizophrenia)
Apoptotic response	Cancer, neurodegenerative disorders (i.e., ALS, Alzheimer's disease Parkinson's disease)
Membrane trafficking	Neurodegenerative disorders (i.e., Parkinson's disease)
Autophagy	Cancer, neurodegenerative disorders (i.e., prion disease, Alzheimer's disease, Huntington's disease)