Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Jun 6;3:91. doi: 10.3389/fneur.2012.00091

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2012 Travo, Gaboyard-Niay and Chabbert.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.

PMC Copyright notice

PMA potentiates vestibular synapse formation in vitro. Eighteen DIV co-cultures of P6 rat ganglion (G), utricle (U), and crista (C) in presence of PMA (A–E) illustrates the potentiation of neurite outgrowth and synapse formation in vitro. Insets show higher magnification of utricles (B,C) and cristae (D,E). Multiple neurites were observed inside the utricles and detailed observation [inset, (B)] on nerve endings reconstructed in 3D (C) showed the additional formation of calyceal innervations in utricles. In cristae, PMA increased the number of neurites entering the sensory epithelia (D), and the number of calyces as shown in the 3D reconstruction (E). Neurofilaments stained in green and nuclei in red. Scale bar 100 μm (A).