Table 1. Examples of hypertension and sex status differences in heritabilities (H2r) of studied traitsa.
Males |
Females |
Normotensives |
Hypertensives |
All |
||||||
---|---|---|---|---|---|---|---|---|---|---|
Trait | N | H2r | N | H2r | N | H2r | N | H2r | N | H2r |
HRb | 134 | 0.67 | 131 | 0.76 | 141 | 0.87 | 124 | 0.34 | 265 | 0.58 |
DBPb | 134 | 0.53 | 133 | 0.25 | 141 | 0.69 | 126 | 0.33 | 267 | 0.41 |
SBPb | 134 | 0.54 | 133 | 0.66 | 141 | 0.48 | 126 | 0.10 | 267 | 0.42 |
Current vs. non-tobacco users | 377 | 0.39 | 320 | 0.62 | 323 | 0.26 | 374 | 0.45 | 697 | 0.39 |
Former vs. never tobacco users | 291 | 0.56 | 224 | 0.81 | 216 | 0.71 | 299 | 0.43 | 515 | 0.61 |
Current vs. former tobacco users | 187 | 0.23 | 220 | 0.97 | 191 | 0.18 | 216 | 0.62 | 407 | 0.46 |
Alcohol use | 377 | 0.85 | 321 | 0.63 | 326 | 0.51 | 372 | 0.55 | 698 | 0.59 |
Abbreviations: DBP, diastolic blood pressure; H2r, heritability; HR, heart rate; SBP, systolic blood pressure.
Bold and underlined numbers indicate the presence of heritability differences between subgroups (e.g., between males and females).
The heritability estimates of all studied traits are presented in Supplementary Table S4.
Average of sitting.