Table 1.
Human G protein-coupled receptors (GPCRs) with putative ciliary localization sequences in the predicted i3 and C-tail domains that are conserved in mouse. Known ciliary GPCRs are indicated
| G protein-coupled receptor | i3 sequence(s) | C-tail sequence(s) | Localization |
|---|---|---|---|
| Beta-1-adrenergic receptor | ALREQ | LEP | ? |
| Cadherin EGF LAG seven-pass G-type receptor 2 | AAQRQ | LNP | ? |
| Dopamine receptor 1 | AKNCQ | LCP/LIP/LSP | ? |
| GPR15 | AHYQQ | LCP | ? |
| GPR54 | ALQGQ | VCP | ? |
| GPR75 | ASRPQ/ASRLQ | LSP | ? |
| GPR92 | ATQSQ | LRP | ? |
| GPR123 | ASVLQ | LSP | ? |
| Melanin-concentrating hormone receptor 1 | APASQ | VKP | Ciliary |
| Opsin 1 (short-wave sensitive) | AVAAQ | VGP | Ciliary |
| Opsin 1 (medium-wave sensitive 2) | AVAKQ | VSP | Ciliary |
| Opsin 1 (long-wave sensitive) | AVAKQ | VSP | Ciliary |
| Rhodopsin | AAAQQ | VAP | Ciliary |
| Serotonin receptor 6 | AARKQ | VLP/LPP/LLP | Ciliary |
| Somatostatin receptor 3 | APSCQ | LRP/LLP | Ciliary |