Figure 2.

(A, B) The ventral anterior cingulate cortex (vACC) is connected with the right amygdala as a function of treatment (acute tryptophan depletion [ATD], placebo) and reward drive (BAS, behavioral activation system; treatment by personality interaction; for angry vs. neutral faces). Slices (x, y) are in the Montreal Neurological Institute space. For display purposes, threshold is set at p < .001, uncorrected; the effects are significant at p < .05, family-wise error, small volume correction. The color bar represents t statistics. (C) Plot of individual data for the local maxima displayed in panels A and B. High-BAS-drive individuals displayed the largest effect of ATD on amygdala-vACC connectivity.