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ORRs to chemotherapy and erlotinib or chemotherapy and placebo according to EGFR gene copy number by FISH
| EGFR FISH (+) | EGFR FISH (−) | |||||
|---|---|---|---|---|---|---|
| Chemotherapy + erlotinib (n = 43) |
Chemotherapy + placebo (n = 57) |
Chemotherapy + erlotinib (n = 78) |
Chemotherapy + placebo (n = 67) |
|||
| ORR | 5 (11.6) | 17 (29.8) | 17 (21.8) | 17 (25.4) | ||
| 95% CI | 4.7–25.0 | 18.4–42.4 | 13.9–32.4 | 15.8–36.8 | ||
| P | 0.0495 | 0.6954 | ||||
All data n (%), unless otherwise noted.
