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. 2011 Dec 23;5(3):356–370. doi: 10.4056/sigs.2194987

Table 4. Number of genes associated with the general COG functional categories.

Code    value    %age    Description
J    176    4.1    Translation, ribosomal structure and biogenesis
A    3    0.1    RNA processing and modification
K    370    8.7    Transcription
L    213    5.4    Replication, recombination and repair
B    2    0.1    Chromatin structure and dynamics
D    35    0.8    Cell cycle control, cell division, chromosome partitioning
Y    0    0.0    Nuclear structure
V    93    2.2    Defense mechanisms
T    393    9.2    Signal transduction mechanisms
M    261    6.1    Cell wall/membrane/envelope biogenesis
N    14    0.3    Cell motility
Z    0    0.0    Cytoskeleton
W    0    0.0    Extracellular structures
U    56    1.3    Intracellular trafficking and secretion, and vesicular transport
O    142    3.3    Posttranslational modification, protein turnover, chaperones
C    205    4.8    Energy production and conversion
G    276    6.5    Carbohydrate transport and metabolism
E    307    7.2    Amino acid transport and metabolism
F    92    2.2    Nucleotide transport and metabolism
H    174    4.1    Coenzyme transport and metabolism
I    128    3.0    Lipid transport and metabolism
P    172    4.0    Inorganic ion transport and metabolism
Q    143    3.4    Secondary metabolites biosynthesis, transport and catabolism*
R    647    15.1    General function prediction only
S    349    8.2    Function unknown
-    1,823    32.2    Not in COGs

* manual annotation yielded 6.4% genes in the secondary metabolites biosynthesis, transport and catabolism category.