Table 2.

 Mean Beck depression inventory (BDI) score and differences in means at four month follow-up of adults with depression allocated to usual care plus facilitated physical activity or to usual care only

Study arm	No	Mean (SD) BDI score	Difference in means* (95% CI), P value
			ITT estimate	MICE estimate	ITT estimate adjusted for practice clustering	ITT estimate adjusted for clustering by PAF	CACE estimate
Intervention	142	16.12 (11.34)	−0.54 (−3.06 to 1.99), 0.68	−0.76 (−3.37 to 1.84), 0.56	−0.54 (−3.06 to 1.99), 0.67	−0.53 (−3.00 to 1.95), 0.68	−0.86 (−4.85 to 3.13), 0.67
Usual care	146	16.87 (12.63)

ITT=intention to treat; MICE=multiple imputation chained equation; PAF=physical activity facilitator; CACE=complier-average causal effect.

*Adjusted for baseline Beck depression inventory score, antidepressant use, severity of depression, level of physical activity, and recruiting centre.