Table 3.
Circulating levels of cytokines in control subjects and in patients with hypertrophic cardiomyopathy
| Cytokines | Control subjects (n=17) |
Patients with HCM (n=24) |
||
| Mean±SD | Range | Mean±SD | Range | |
| hsCRP, mg/l | 1.29±1.50 | 0.09–5.69 | 4.93±8.38** | 0.33–38.90 |
| TNFα, pg/ml | 2.33±1.22 | 1.38–6.43 | 3.24±−2.98 | 1.56–16.50 |
| IL-1β, pg/ml | 0.18±0.08 | 0.09–0.34 | 0.32±0.25* | 0.09–1.00 |
| IL- 1RA, pg/ml | 216±76 | 101–391 | 490±577** | 194–3023 |
| IL-6, pg/ml | 1.11±0.72 | 0.38–2.80 | 2.15±1.67** | 0.75–7.55 |
| IL-10, pg/ml | 0.86±0.55 | 0.49–2.04 | 2.98±4.04*** | 0.49–20.86 |
*p<0.05; **p<0.01; ***p<0.001.
hsCRP, high-sensitivity C-reactive protein; IL-1β, interleukin 1β; IL- 1RA, interleukin 1 receptor antagonist; IL-6, interleukin 6; IL-10, interleukin 10; TNFα, tumour necrosis factor α.