Table 2.
Symptomatic (n = 6) | Asymptomatic (n = 13) | P value | ||
---|---|---|---|---|
Plaque | PON lactonase activity (U/mg proteins) | 0.16 ± 0.035 (n = 8) | 0.18 ± 0.054 (n = 9) | N.S. |
Triglyceride (% of LLE) | 3.4 ± 1.07 | 2.37 ± 0.37 | N.S. | |
7-keto (% of cholesterol) | 0.38 ± 0.19 | 0.25 ± 0.05 | N.S. | |
26-OH (% of cholesterol) | 1.16 ± 0.27 | 1.29 ± 0.19 | N.S. | |
7α-OH (% of cholesterol) | 0.087 ± 0.015 | 0.085 ± 0.01 | N.S. | |
7β-OH (% of cholesterol) | 0.075 ± 0.01 | 0.08 ± 0.009 | N.S. | |
β-epoxy (% of cholesterol) | 0.096 ± 0.01 | 0.114 ± 0.02 | N.S. | |
α-epoxy (% of cholesterol) | 0.055 ± 0.004 | 0.069 ± 0.008 | N.S. | |
LA-13OOH (μg/mg plaque) | 0.012 ± 0.002 | 0.0053 ± 0.0009 | 0.019 | |
| ||||
Serum | PON1 lactonase activity (U/mL) | 38 ± 3.2 | 45 ± 2.9 | N.S. |
HbA1c (%) | 7.17 ± 0.48 | 6.04 ± 0.15 | 0.065 | |
HDL (mg/dL) | 37.8 ± 3.35 | 51.7 ± 3.06 | 0.009 | |
LDL (mg/dL) | 79 ± 13.2 | 90.9 ± 4.4 | N.S. | |
Cholesterol (mg/dL) | 158.6 ± 11.2 | 168.08 ± 6.4 | N.S. | |
Triglyceride (mg/dL) | 164.8 ± 27 | 127.2 ± 15.2 | N.S. |
LLE: lesion lipid extract. Results are presented as mean ± SEM.