Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Antipsychotic drugs inhibit dauer formation and decrease lifespan. (A) Clozapine (80 and 160 μM) and olanzapine (80 and 160 μM) inhibited dauer formation under dauer-inducing conditions. The number of dauer larvae per 1000 L3-adult stage animals is shown for each condition. (B) Olanzapine decreased the lifespan of wild type animals, but not in a daf-2 background. The percent of animals surviving at 25 °C is plotted as a function of time. Drug concentrations are provided in Methods.
