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Distribution of THLE Cv of drugs and candidates as measured by an ATP depletion assay. Results are color-coded by high cell viability (IC50 > 100 μM, green) and low cell viability (IC50 ≤ 100 μM, red). (A) Overall distribution of THLE Cv for the drug and candidate set. (B) Segregation of THLE Cv data into high and low lipophilicity bins.
