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ADME attribute alignment of drugs and candidates, color-coded by the count of achieving the following criteria: high permeability (Papp > 10 × 10−6 cm/s), low P-gp liability (≤ 2.5), and low clearance (CLint,u ≤ 100 mL/(min·kg)). Colors are as follows: full alignment with 3/3 attributes achieved (green), 2/3 attributes achieved (yellow), 1/3 attributes achieved (red), 0/3 attributes achieved (gray).
