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. 2010 Mar 25;1(6):420–434. doi: 10.1021/cn100007x

Table 2. Candidates by Target.

candidate count target mechanism target family
13 enzymes enzymes
4 cannabinoids GPCR
13 dopaminergic GPCR GPCR
2 histaminergic GPCR GPCR
2 muscarinic GPCR
4 opioids GPCR
13 peptide GPCR GPCR
16 serotonergic GPCR GPCR
6 calcium channel ion channels
11 GABA receptors ligand-gated ion channel
5 glutamate receptors ligand-gated ion channel
8 nicotinic ligand-gated ion channel
11 reuptake inhibitors transporters