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. 2010 May 25;1(7):476–481. doi: 10.1021/cn100031t

Figure 1.

Figure 1

Structures of isoform-selective, allosteric Akt inhibitors. The structures of the potent dual Akt1/Akt2-selective (1), Akt1-selective (2), and Akt2-selective (3) inhibitors are shown. IC50 for each Akt isoform is shown for each compound.