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. Author manuscript; available in PMC: 2012 Jun 6.
Published in final edited form as: J Cell Sci. 2006 Jan 1;119(Pt 1):4–10. doi: 10.1242/jcs.02746

Fig. 1.

Fig. 1

Mammalian septins localize to the plasma membrane and with the actin and microtubule cytoskeletons. (A,B) SEPT2 localizes to the cell cortex, the microtubule spindle apparatus and the midbody of mammalian cells (MDCKs) in mitosis. (C) SEPT2 (red) localizes to membranes (green) labeled with gpiYFP (glycosylphosphatidylinositol linked to yellow fluorescence protein) in interphase MDCK cells. The outlined area shows a region of cell-cell contact in which SEPT2 elements are closely apposed to the plasma membrane. (D) SEPT2 elements (green) colocalize with the microtubule (blue; arrow heads) and actin (red; arrows) cytoskeletons in interphase MDCK cells. All images represent ~1 μm optical sections obtained by confocal microscopy. Bars, ~10 μm.