Table 4.

Overview of the data collection from visit 1 to visit 7

Setting	Inpatient intervention		Outpatient follow-ups			(In/)outpatient follow-ups
VISIT	VISIT 1	VISIT 2	VISIT 3	VISIT 4	VISIT 5	VISIT 6	VISIT 7
Time point	Intervention start	Intervention end	1/2 y	1 y	2 y	5 y	10 y
Physical examination
Anthropometry*	+	+	+	+	+	+	+
Pubertal stage (Tanner)	+		+	+	+	+	+
Comorbidities/Medication	+	+	+	+	+	+	+
Genetic and blood parameters
Collection of EDTA	+
All blood parameters**	+	+				(+)	(+)
HDL, LDL, total cholesterol, triglycerides, glucose	+	+				+	+
Physical fitness and activity
Physical fitness (ergometry)	+	+				(+)	(+)
6-Minutes running test	+	+				(+)	(+)
Pedometer***	+					(+)	(+)
Questionnaires (filled in by children)
Quality of life (KINDL)	+	+	+	+	+	+	+
Diet/Dietary intake	+	+	+	+	+	+	+
Physical activity	+	+	+	+	+	+	+
Questionnaire (filled in by parents)
Family background	+

*body weight, body height, waist circumference, blood pressure.

**HDL, LDL, total cholesterol, triglycerides, glucose, proinsulin, insulin, uric acid, TSHbasal, adiponectin, leptin, RBP-4, resistin, high sensitive CRP, IL-6, TNFα.

***subgroup analysis.