Table 1.
Statistics for demographic, cognitive, and brain volumetry variables for the non-cognitive impaired participants (NCI, N = 40) and mild cognitively impaired participants (MCI, N = 40)
| NCI n = 40 |
MCI n = 40 |
Whole sample n = 80 |
t or χ2 | p value | |
|---|---|---|---|---|---|
| Age (years) | |||||
| Mean (SD) | 86.28 (4.39) | 86.26 (4.49) | 86.27 (4.41) | .025 | .98 |
| Range | 74–94 | 75–94 | 74–94 | ||
| Education (years) | |||||
| Mean (SD) | 15.98 (2.86) | 15.00 (3.22) | 15.49 (3.07) | 1.43 | .16 |
| Range | 12–23 | 8–25 | 8–25 | ||
| MMSE (total score)*** | |||||
| Mean (SD) | 28.68 (1.23) | 27.10 (1.96) | 27.59 (1.81) | 4.31 | <.001 |
| Range | 26–30 | 23–30 | 23–30 | ||
| Sex | |||||
| % Female | 62.5 (n = 25) | 82.5 (n = 33) | 72.5 (n = 58) | 3.07 | .08 |
| Race | |||||
| % White | 100(n = 40) | 100(n = 40) | 100(n = 80) | - | - |
| Global Cognition (z-score)*** | 0.49 (0.41) | −0.18 (0.50) | 6.59 | <.001 | |
| Episodic Memory (z-score)*** | 0.68 (0.52) | −0.23 (0.85) | 5.74 | <.001 | |
| Semantic Memory (z-score)*** | 0.56 (0.63) | −0.07 (0.75) | 4.02 | <.001 | |
| Working Memory (z-score)** | 0.31 (0.73) | −0.16 (0.83) | 2.69 | .009 | |
| Processing Speed (z-score)** | 0.25 (0.63) | −0.16 (0.73) | 2.70 | .008 | |
| Perceptual Organization (z-score)*** | 0.45 (0.53) | −0.33 (0.91) | 4.64 | <.001 | |
| Total Gray Matter (mm3) | 268.10 (26.85) | 270.34 (21.03) | 20.42 | .68 | |
| Posterior Cingulate Cortex (mm3) | 2.98 (0.60) | 3.04 (0.57) | 20.49 | .62 |
Note. Data are summarized as Mean (standard deviation = SD) or as number (%). Age and education are presented in years; MMSE is total score; global cognition, episodic memory, semantic memory, working memory, processing speed, and perceptual organization are presented as z-scores; and total gray matter and posterior cingulate cortex volumes are presented as mm3. Asterisks indicate significant differences between diagnostic groups.
**
p<.01
***
p<.001.