Table 3.
Results of voxel-wise, between-group contrasts of z-transformed functional connectivity values (MCI versus NCI) while accounting for the effects of total gray matter volume
| Location of Maximum Intensity Voxel |
# Voxels | MNI Coordinates | t-value | ||
|---|---|---|---|---|---|
| NCI>MCI | |||||
| L orbital frontal | 13 | −48 | 30 | −12 | 4.2153 |
| R orbital frontal | 8 | 45 | 30 | −12 | 3.9043 |
| R middle frontal | 5 | 24 | 42 | −15 | 3.8609 |
| L putamen | 52 | −24 | −6 | 12 | 4.9792 |
| R caudate 1 | 7 | 18 | 27 | 6 | 4.1524 |
| R caudate 2 | 22 | 21 | −12 | 18 | 4.0735 |
| L superior temporal | 10 | −54 | −48 | 15 | 3.9342 |
| R posterior cingulate | 13 | 12 | −42 | 18 | 4.7002 |
| MCI>NCI | |||||
| L fusiform | 5 | −45 | −27 | −27 | 4.6011 |
| L rectal | 7 | −6 | 30 | −27 | 3.9158 |
| R inferior frontal | 12 | 60 | 12 | 24 | 3.8467 |
| L precentral | 6 | −57 | −9 | 36 | 4.1251 |
To control for multiple comparisons and spurious findings, we used the following consistent with our within-group false discovery rate threshold: p<.001, cluster size >5 voxels.