Table 3.
Correlations among white matter fractional anisotropy, treatment, and substance use
| Prefrontal | Orbitofrontal | Parietal | Temporal | Corpus callosum | |
|---|---|---|---|---|---|
| Current conduct disorder (yes/no) | −.39* | −.37* | −.22 | −.33 | −.16 |
| Full scale IQ score | .09 | .12 | .24 | .29 | −.17 |
| Age at regular alcohol use | .50** | .36 | .08 | .23 | .04 |
| Age at regular marijuana use | .22 | .21 | .24 | .25 | .09 |
| BL Alcohol Motivation to Abstain | −.49** | −.48** | −.11 | −.46* | −.15 |
| BL Marijuana Motivation to Abstain | .03 | −.27 | .20 | .17 | − −.12 |
| Treatment days attended | .21 | .02 | −.08 | .13 | .06 |
| Alcohol abstinent days pre-scan | −.13 | −.06 | −.15 | −.01 | −.12 |
| Marijuana abstinent days pre-scan | .12 | −.06 | .09 | .04 | −.10 |
| Alcohol use days prior to scan | .14 | .13 | .09 | .19 | −.03 |
| Marijuana use days prior to scan | .12 | .32 | .00 | .00 | .40* |
| Alcohol frequency at 6-months | −.12 | .00 | −.20 | −.17 | .01 |
| Marijuana frequency at 6-months | −.01 | .18 | .03 | −.06 | .35 |
| 6-month RAPI score | −.49** | −.45* | −.42* | −.47* | −.58** |
| 6-month RMPI score | −.23 | −.17 | −.04 | −.01 | −.30 |
| Total number of drinks at 6-mo | −.13 | −.23 | −.37* | −.36* | −.22 |
Notes: Ns range from 26–32 due to missing data for certain items.
p<.05,
p≤.01.
Current=past 6 months. BL Alc/MJ Motiv=Baseline motivation to abstain from alcohol/marijuana in the next 30 days. Treatment days= number of treatment days attended from the start of intensive outpatient treatment to scan day. Alcohol/Marijuana use days prior to scan=number of days of use in the 30 days prior to imaging. 6-mo: 6-month follow-up. RAPI/RMPI=Rutgers Alcohol/Marijuana Problems index at 6-months. Total drinks 6-mo= total number of drinks in the past 30 days at 6-month follow-up.