Figure 3.

During waking, [oxy] in cortical areas activated by movement increases more when locomotor activity is high, whereas [lac] or [glu] do not change in association with locomotor activity. Each panel depicts the concentration (mean ± standard error of the mean) of lactate (A), oxygen (B), or glutamate (C) in 4-sec epochs across all episodes of mostly active or mostly quiet wake. All episodes were classified as either active or quiet based on total electromyographic activity across the duration of the wake episode. *P < 0.01. Glutamate results were derived from data previously collected by Dash et al.¹⁸