Figure 5. CCL2 deficiency does not affect aminotransferase levels and inflammation following administration of an MCD diet in C57Bl/6 mice.

WT or CCL2-KO mice were fed for 8 weeks on the control diet or the MCD diet. Groups are as in the legend to Figure 1. (A) Serum ALT was assayed as described in Materials and methods section. (B) Individual necro-inflammatory scores in the four groups of mice. (C) RNA was isolated from liver tissue, and expression of CD11b was measured by RT-PCR. U, units.