Table 1.

Changes in the antiparkinsonian medication and the behavior of the patient

Time after diagnosis years	Medication, daily dose	Non-motor behavioral changes
0	Diagnosis of Parkinson's disease, selegiline 5 mg	–
1	Selegiline 5 mg, cabergoline 1 mg	–
2	Selegiline 5 mg, cabergoline 2 mg	–
3	Selegiline 5 mg, cabergoline 2 mg, levodopa/carbidopa 100/25 mg	–
5	Selegiline 10 mg, cabergoline 2 mg, levodopa/carbidopa 200/50 mg	Pathological gambling, punding
7	Selegiline 10 mg, cabergoline 2 mg, levodopa/carbidopa 200/50 mg	Creativity, pathological gambling, punding
9	PET imaging, selegiline 10 mg, cabergoline 2 mg, levodopa/carbidopa 300/75 mg	Creativity, pathological gambling, punding
10	Selegiline 10 mg, pramipexole 0.18 mg, levodopa/carbidopa/entacapone 750/187.5/1,000 mg under consideration for deep brain stimulation	Creativity, punding