Table 1.

Functional clustering of differentially expressed genes in Smo-depleted OP9

Category term*	Feature†	Count‡	Enrichment score§
Glycoprotein	Glycosylation, signal peptide, extracellular region	116	10.25
Pattern recognition	Polysaccharide, heparin, pattern binding	14	4.45
Extracellular matrix	Extracellular region and matrix	28	3.72
Cell adhesion	Biological, cell, and cell-cell adhesion	21	3.16
Oxidation reduction	Oxidation reduction and oxidoreductase	22	3.08

DAVID functional clustering^26,27 was performed on 264 genes (206 down-regulated, 58 up-regulated) displaying a 2-fold or greater change with P < .001.

^*General DAVID functional category.

^†General DAVID functional annotation term.

^‡Number of genes indentified in functional cluster.

^§Enrichment score was determined by EASE.^26,27