Figure 3. Network and polymorphism analyses on catalytic domain of cruzipain genes from different trypanosome species.

Genes from Schizotrypanum species (T. cruzi, T. c. marinkellei and T. dionisii) were compared with homologues from their closest relative species, T. rangeli, and the distant related T. b. brucei. (A) Network of 33 amino acid predicted sequences constructed using the Neighbour-Net algorithm excluding all conserved sites and with Uncorrected p-distance. The numbers in nodes correspond to bootstrap values from 100 replicates. (B) Polymorphism on cruzipain amino acid sequences from the distinct trypanosome species.