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. 2012 Jun 7;8(6):e1002528. doi: 10.1371/journal.pcbi.1002528

Table 2. The top 10 pairs-gene knockouts or over-expressions that maximize the agronomic properties of the tomato fruit.

Gene Gene Annotation Efficiency Inline graphic 1
Acceptability
LE33G22; LE28J07 Adenylate kinase, putative; vesicle-associated membrane protein, putative 16.54
LE15D09; LE33G22 Vesicle-associated membrane protein, putative; adenylate kinase, putative 16.54
LE17M21; LE33G22 Selenoprotein O, putative; adenylate kinase, putative 16.40
LE17D17; LE33G22 F-box family protein; adenylate kinase, putative 16.37
LE15E19; LE33G22 Ribosomal protein; adenylate kinase, putative 16.07
LE7I21; LE33G22 Proline-rich cell wall protein-like; adenylate kinase, putative 15.90
LE33G22; LE23K21 Adenylate kinase, putative; amino acid transporter, putative 15.87
LE33G22; LE2C08 Adenylate kinase, putative; chloroplast lumen common family protein 15.85
LE33G22; LE25J09 Adenylate kinase, putative; AT-HSFA6B, DNA binding/transcription factor 15.84
LE33G22; LE24D10 Adenylate kinase, putative; not found 15.78
Quality (aroma and taste)
LE27F15; LE29L05 Protein kinase family protein; branched-chain amino acid aminotransferase 422.60
LE16D08; LE6G08 Similar to 60S ribosomal protein L35; sucrose phosphate synthase 360.63
LE9A08; LE15E23 GRAM domain-containing protein/ABA-responsive protein-related; putative threonyl-tRNA synthetase 303.04
LE18E13; LE8A19 MYB transcription factor; putative glycerophosphoryl diester phosphodiesterase family protein 263.91
LE32B05; LE4D06 YABBY2-like transcription factor YAB2; tRNA-dihydrouridine synthase A, putative 253.33
LE15L08; LE4J06 Putative rac protein; 50S ribosomal protein L27, chloroplastic 244.32
LE29E13; LE13F06 Fyve finger-containing phosphoinositide kinase, fyv1, putative; transmembrane protein, putative 242.56
LE13F06; LE15J03 Transmembrane protein, putative; ankyrin-like protein 240.19
LE17G02; LE15D07 Pantothenate kinase, putative; polynucleotide kinase- 3′-phosphatase, putative 239.10
LE15D07; LE20I03 Polynucleotide kinase- 3′-phosphatase, putative; DEX1, calcium ion binding 239.03
Quality vs production
LE13F06; LE15J03 Transmembrane protein, putative; ankyrin-like protein 49.79
LE12O13; LE33G22 Prefoldin subunit, putative; adenylate kinase, putative 49.16
LE2C24; LE29J02 ATAB2; RNA binding; GTP-binding protein LepA homolog 49.15
LE12P11; LE2C24 Not found; ATAB2; RNA binding 48.81
LE2C24; LE21J01 ATAB2; RNA binding; Dolichyl-phosphate beta-glucosyltransferase, putative 48.28
LE12O13; LE25M06 Prefoldin subunit, putative; Pre-mRNA-processing protein prp39, putative 46.63
LE12O13; LE14B20 Prefoldin subunit, putative; clathrin adaptor complexes medium subunit family protein 46.18
LE14B20; LE21J01 Clathrin adaptor complexes medium subunit family protein; dolichyl-phosphate beta-glucosyltransferase, putative 44.86
LE33B09; LE2C24 Not found; ATAB2; RNA binding 44.64
LE18M21; LE14B20 Cysteine protease; clathrin adaptor complexes medium subunit family protein 44.05
1

Efficiencies were selected in the RIL where the perturbation maximizes the fruit acceptability, quality and, quality vs production (RILs 103, 142, and 135, respectively).

Knockout genes were showed in bold type and the others were gene over-expressed.