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. 2012 Jun 7;8(6):e1002689. doi: 10.1371/journal.pgen.1002689

Table 1. Clonal Mitochondrial DNA Mutations Identified in Colorectal Tissue.

Patient ID Tissue Gene DNA Protein
2 Carcinoma COXII 7859G>A D92N
COXIII 9451G>A G82E
4 Carcinoma non-coding 5894insC
Cyt b 15375G>A G210E
5 Carcinoma D-loop 508A>G
6 Carcinoma COXIII 9645G>A A147T
7 Carcinoma D-loop 523delAC
12S rRNA 1598G>A
ND2 4707C>T L80F
10 Carcinoma ND4L 10675G>A C69Y
ND5 13239C>A I301M
D-loop 16465C>T
11 Carcinoma D-loop 72T>C
D-loop 309insC
COXI 6121T>C I73T
COXIII 9439G>A G78D
17 Carcinoma ND5 12426insA frameshift
D-loop 16298C>T
D-loop 16390G>A
18 Carcinoma ND1 3745G>A A147T
ND5 13133delT frameshift
19 Carcinoma ND5 13970G>A S545N
20 Carcinoma D-loop 524insAC
16S rRNA 2957G>A
18 Adenoma ND5 13193T>C L286P
19 Adenoma D-loop 66delG
ND1 4142G>A R279Q
COXII 8251G>A
ND4 11711G>A A318T
D-loop 16183insC
20 Adenoma D-loop 524insAC
16S rRNA 2957G>A
69 Adenoma ND1 3571insC frameshift
ND2 5450C>T
70 Adenoma tRNA M 4465T>C
Cyt b 15448C>T
74 Adenoma 12S rRNA 1045G>A
COXII 8141G>A A186T
ND4 10952insC frameshift
D-loop 16166A>G
D-loop 16309A>G