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. 2012 Jun 7;18(21):2730–2734. doi: 10.3748/wjg.v18.i21.2730

Table 2.

Clinical characteristics and outcomes of infliximab treatment in 5 Crohn’s disease patients with severe gastrointestinal bleeding as a first presentation

No. Age (yr) Sex Presenting symptom Dropped rate of Hb (g/dL) PRBC (unit) Location Characteristic of lesion Infliximab therapy Bleeding controlled in Follow-up (mo)
1 59 M Diarrhea and abdominal pain (10 d) GIB (1 d) from 10 to 8 in 3 d 6 Ileum Multiple ileal ulcers with oozing and one visible vessel Infliximab 5 mg/kg (d0, week 2) 1 d 24
2 86 M GIB (1 d) from 12 to 8.5 in 4 d 7 Ileum Multiple ileal ulcers with oozing Infliximab 5 mg/kg (d0, week 2) 1 d 36
3 71 F Diarrhea and abdominal pain (10 d) GIB from 13 to 10 in 3 d 3 ileum Multiple ileal ulcers with oozing Infliximab 5 mg/kg (d0, week 2) 1 d 12
4 50 yr F Diarrhea and abdominal pain (14 d) GIB (1 d) from 14 to 10 in 3 d 2 Ileum and jejunum Multiple ileal and jejunum ulcers with oozing Infliximab 5 mg/kg (d0, week 2) 1 d 36
5 71 yr M 1st episode GIB from ileal ulcer (1 mo)Recurrent GIB (1 d) from 11 to 6.5 in 5 d 6 Ileum Multiple ileal ulcers with oozing and one visible vessel Infliximab 5 mg/kg (single dose ) 1 d 24

CD: Crohn’s disease; GIB: Gastrointestinal bleeding; Hb: Hemoglobin; 5-ASA: 5-aminosalicylates; PRBC: Packed red blood cell; M: Male; F: Female.