Table 2.
Clinical characteristics and outcomes of infliximab treatment in 5 Crohn’s disease patients with severe gastrointestinal bleeding as a first presentation
| No. | Age (yr) | Sex | Presenting symptom | Dropped rate of Hb (g/dL) | PRBC (unit) | Location | Characteristic of lesion | Infliximab therapy | Bleeding controlled in | Follow-up (mo) |
| 1 | 59 | M | Diarrhea and abdominal pain (10 d) GIB (1 d) | from 10 to 8 in 3 d | 6 | Ileum | Multiple ileal ulcers with oozing and one visible vessel | Infliximab 5 mg/kg (d0, week 2) | 1 d | 24 |
| 2 | 86 | M | GIB (1 d) | from 12 to 8.5 in 4 d | 7 | Ileum | Multiple ileal ulcers with oozing | Infliximab 5 mg/kg (d0, week 2) | 1 d | 36 |
| 3 | 71 | F | Diarrhea and abdominal pain (10 d) GIB | from 13 to 10 in 3 d | 3 | ileum | Multiple ileal ulcers with oozing | Infliximab 5 mg/kg (d0, week 2) | 1 d | 12 |
| 4 | 50 yr | F | Diarrhea and abdominal pain (14 d) GIB (1 d) | from 14 to 10 in 3 d | 2 | Ileum and jejunum | Multiple ileal and jejunum ulcers with oozing | Infliximab 5 mg/kg (d0, week 2) | 1 d | 36 |
| 5 | 71 yr | M | 1st episode GIB from ileal ulcer (1 mo)Recurrent GIB (1 d) | from 11 to 6.5 in 5 d | 6 | Ileum | Multiple ileal ulcers with oozing and one visible vessel | Infliximab 5 mg/kg (single dose ) | 1 d | 24 |
CD: Crohn’s disease; GIB: Gastrointestinal bleeding; Hb: Hemoglobin; 5-ASA: 5-aminosalicylates; PRBC: Packed red blood cell; M: Male; F: Female.