Table 5.

Protein expression in initial mucosal melanoma and survival

Protein expression (N = 45)a	Overall survival (median in years)	Disease specific survival (median in years)
bcl-2
Negative (12)	1.36 (P = 0.03)	1.54 (P = 0.02)
Positive (33)	2.6	3.3
p53
Negative (22)	2.60 (P = 0.82)	3.30 (P = 0.75)
Positive (23)	1.65	2.29
p16
Negative (30)	1.5 (P = 0.27)	2.38 (P = 0.58)
Positive (15)	3.01	3.01
bcl-2+/p16+/p53− (6)	3.30 (P = 0.17)	3.30 (P = 0.17)
bcl-2−/p16−/p53+ (4)	1.54	1.54

^aSurvival information was available in 45 initial mucosal melanomas