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Effect of LIF supplementation on IL-6 induction in vitro. IL-6 mRNA induction was determined in alveolar macrophages (AM), RAW 264.7 cells and MLE-12 cells following 2 hrs of LPS stimulation in the absence and presence of recombinant murine LIF (rmLIF). Data are expressed as fold-induction compared to cells not treated with LPS. Means ± SEM were calculated by combining data from 3 separate experiments or 3 individual mice (n = 3).
