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. Author manuscript; available in PMC: 2013 Jun 15.
Published in final edited form as: J Immunol. 2012 May 4;188(12):5970–5980. doi: 10.4049/jimmunol.1200452

FIGURE 5.

FIGURE 5

Lin−c-Kit+CX3CR1− cell subset expresses megakaryocyte progenitor genes. (A) Flow cytometry of c-Kit+ (CD117+) cells for CX3CR1marker in CD90−CD19− splenocytes of SNF1 mice. (B–C) The subsets of c-Kit+ cells (APC) were isolated by sorting (designated by color key) and then analyzed for inducing IFN-γ (B) and IL-17 responses (C) in SNF1 T cells to nucleosomes. Mean ± s.e.m. of 5 independent experiments. (D) Microarray analysis (average of triplicates): Each row represents a gene and each column represents each APC type. L−K+Cx− = Lin−c-Kit+CX3CR1− cells; L−K+Cx+ = Lin−c-Kit+CX3CR1+ cells; DC = dendritic cells. Genes with highly significant changes (3–22 fold, P as low as 0.000000000044) are shown.