Table 1.
Characteristics and mean responses to carboplatin and cisplatin of the HapMap panels included in the meta-analyses.
| YRI1/2 | YRI3 | ASW | CHD | ASN | CEU1/2 | CEU3 | |
|---|---|---|---|---|---|---|---|
| N | 90 | 86 | 83 | 85 | 90 | 90 | 84 |
| family structure |
30 trios | 27 trios, 1 duo, 3 singletons |
10 trios, 20 duos, 13 singletons |
unrelated | unrelated | 30 trios | 22 trios, 5 duos, 8 singletons |
| carboplatin IC501 (μM) |
30.0 (17.4) | 36.8 (14.1) | 20.1 (7.1) | 25.1 (23.7) | 19.7 (8.2) | 24.5 (13.9) | 28.2 (14.0) |
| cisplatin IC501 (μM) |
8.3 (6.5) | 10.2 (6.1) | 4.6 (4.1) | 6.7 (11.5) | 4.5 (3.7) | 7.8 (8.5) | 8.1 (5.6) |
mean (SD)