Table 1.

These matrix equations transform simple morphologic measurements into PBPK model parameters used in this experiment. For example, a male, 29.3 yr old, 171 cm, 93.6 Kg subject would have a PBPK peripheral body water volume parameter, Vp(L), equal to (−12.414*1.0) − (0.054*29.3) + (0.132*171) + (0.303*93.6) = 36.8 liters. Height is measured with no shoes; weight with no shoes or jacket and nothing in the pockets.