TABLE 2.
Tn | ATPase pCa50a | ATPase Ca2+ sensitivity | Hill coefficient | Maximal ATPase activityb | Minimal ATPase activityc |
---|---|---|---|---|---|
μm | |||||
Control | 5.81 ± 0.03 | 1.6 ± 0.1 | 1.18 ± 0.09 | 0.037 ± 0.003 | 0.0072 ± 0.0006 |
TnI R192H | 6.29 ± 0.03* | 0.52 ± 0.04* | 1.1 ± 0.1 | 0.029 ± 0.003 | 0.0110 ± 0.0008* |
TnC S69D | 5.27 ± 0.07* | 5.6 ± 0.9* | 1.0 ± 0.2 | 0.035 ± 0.003 | 0.010 ± 0.002 |
TnI R192H-TnC S69D | 5.84 ± 0.09 | 1.5 ± 0.3 | 0.83 ± 0.08* | 0.038 ± 0.002 | 0.012 ± 0.001* |
a The Ca2+ concentration at half-maximal ATPase activity.
b Maximal ATPase activity [mol of phosphate s−1 (mol of S1)−1].
c Minimal ATPase activity [mol of phosphate s−1 (mol of S1)−1].