TABLE 3.
Summary of skinned trabecula force generation
Values marked with* are significantly different from the control values (p < 0.05). NA denotes a measurement that is not applicable.
| Tn | pCa50a | Hill Coefficient | % of force recovery | % of active tension at pCa 9.0 |
|---|---|---|---|---|
| Endogenous | 5.67 ± 0.06 | 5 ± 2 | NA | 9 ± 3 |
| Mock exchange | 5.76 ± 0.07 | 1.8 ± 0.3 | 68 ± 5 | 1 ± 1 |
| Control | 5.74 ± 0.06 | 2.2 ± 0.2 | 55 ± 7 | 1 ± 2 |
| TnI-(1–192) | 6.8 ± 0.1* | 1.3 ± 0.1* | 86 ± 8* | 21 ± 4* |
| TnI-(1–192)-TnCS69D/D73N | 5.88 ± 0.05 | 1.5 ± 0.1* | 70 ± 6 | 7 ± 4 |
| TnT ΔK210 | 5.35 ± 0.02* | 2.7 ± 1.0 | 51 ± 4 | 0 ± 1 |
| TnT ΔK210-TnCM45Q/S69D | 5.74 ± 0.04 | 2.4 ± 0.3 | 52 ± 3 | 5 ± 1 |
a The Ca2+ concentration at half-maximal force.